Innovation in bone healing and tissue repair

Kuros is developing bone graft substitute products for multiple locations in the body.  MagnetOs Granules have been developed for use in many fracture indications and have received marketing approval in Europe for a broad range of indications in the orthopedic, spine and dental areas.  For tibial plateau fractures, KUR-111 aims to provide comparable efficacy to autograft (transplantation of bone from the same individual) but without the associated risks of bone harvesting at another healthy site of the patient’s body. In other indications, like tibial shaft fractures Kuros' fracture repair product candidates aim to address new markets by improving the efficacy of bone repair in indications where bone grafts are not an option.

More than 50 million fractures occur worldwide every year and, in 2010, more than 8 million fracture repair procedures were carried out globally. For more severe fractures, especially complex fractures standard treatment is to manipulate the bone to its correct position minimizing any gaps at the fracture site (this is termed reduction), and then to fixate the bones in place either using plates, screws or nails inside the body (internal fixation) or rods and pins with the rods external to the body/limb (external fixation). If there are any defects or voids once the fracture has been reduced these may require filling with a bone graft or a bone graft substitute, in order to support healing.

The choice of material is dependent on the clinical situation. The orthopedic surgeon has a choice of products available as bone grafts or bone graft substitutes. These differ with respect to efficacy, cost and patient morbidity. Kuros product candidates aim to offer maximum efficacy with no product-related patient morbidity.

 

Kuros Biosciences AG
Wagistrasse 25, 8952 Schlieren, Switzerland
Tel: +41 44 733 47 47   Fax: +41 44 733 47 40   Email: info@kuros.ch

About Kuros

  1. Overview
  2. Management
  3. Board

Products

  1. Pipeline
  2. Orthobiologics
    Fracture repair
    KUR-111
    KUR-113
    MagnetOs
    Spinal fusion
    KUR-113
    MagnetOs
    Solitary Bone Cysts
    KUR-112
  3. Sealants
    Neuroseal (KUR-023)

Technologies

  1. Overview
  2. Surface Science Technology
  3. Synthetic Cross-Linking Technology
  4. Fibrin-Based
  5. Immune Modulation
  6. Publications

Partnerships

  1. Collaborations
  2. Business development

Investors

  1. Share price
  2. Regulatory filings
  3. Reports & presentations
  4. Calendar
  5. Corporate governance
  6. Stay informed

News

  1. Press releases
  2. Conferences & Events

Contact

  1. Location
Fracture repair

Kuros is developing bone graft substitute products for multiple locations in the body.  MagnetOs Granules have been developed for use in many fracture indications and have received marketing approval in Europe for a broad range of indications in the orthopedic, spine and dental areas.  For tibial plateau fractures, KUR-111 aims to provide comparable efficacy to autograft (transplantation of bone from the same individual) but without the associated risks of bone harvesting at another healthy site of the patient’s body. In other indications, like tibial shaft fractures Kuros' fracture repair product candidates aim to address new markets by improving the efficacy of bone repair in indications where bone grafts are not an option.

More than 50 million fractures occur worldwide every year and, in 2010, more than 8 million fracture repair procedures were carried out globally. For more severe fractures, especially complex fractures standard treatment is to manipulate the bone to its correct position minimizing any gaps at the fracture site (this is termed reduction), and then to fixate the bones in place either using plates, screws or nails inside the body (internal fixation) or rods and pins with the rods external to the body/limb (external fixation). If there are any defects or voids once the fracture has been reduced these may require filling with a bone graft or a bone graft substitute, in order to support healing.

The choice of material is dependent on the clinical situation. The orthopedic surgeon has a choice of products available as bone grafts or bone graft substitutes. These differ with respect to efficacy, cost and patient morbidity. Kuros product candidates aim to offer maximum efficacy with no product-related patient morbidity.